| Identification | Back Directory | [Name]
PMMB276 | [CAS]
2209036-28-0 | [Synonyms]
PMMB276
1,3-Dithiane-4-pentanoic acid, 2-phenyl-, (1R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester, (4R)- | [Molecular Formula]
C31H34O6S2 | [MOL File]
2209036-28-0.mol | [Molecular Weight]
566.73 |
| Chemical Properties | Back Directory | [Melting point ]
46-46.8 °C | [Boiling point ]
775.4±60.0 °C(predicted) | [density ]
1.276±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
7.08±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis. PMMB276 plays an important role in cancer research[1]. | [References]
[1] Hongwei Han, et al. A modified natural small molecule inhibits triple-negative breast cancer growth by interacting with Tubb3. Phytomedicine. 2024 Apr:126:154894. DOI:10.1016/j.phymed.2023.154894 |
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