| Identification | Back Directory | [Name]
Lethedioside A | [CAS]
221289-31-2 | [Synonyms]
Lethedioside A
2-(3,4-Dimethoxyphenyl)-7-methoxy-4-oxo-4H-chromen-5-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-methoxy-5-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-
2-(3,4-Dimethoxyphenyl)-7-methoxy-5-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one | [Molecular Formula]
C29H34O15 | [MDL Number]
MFCD20274951 | [MOL File]
221289-31-2.mol | [Molecular Weight]
622.571 |
| Hazard Information | Back Directory | [Description]
Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant. | [Uses]
Lethedioside A is an Enhancer of split 1 (Hes1) dimer inhibitor with an IC50 value of 9.5 μM[1]. | [References]
[1] Midori A Arai, et al. Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells. Chem Sci. 2016 Feb 1;7(2):1514-1520. DOI:10.1039/c5sc03540f |
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