| Chemical Properties | Back Directory | [density ]
1.315±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
10.65±0.10(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
ERK-MYD88 interaction inhibitor 1 is an ERK-MYD88 interaction inhibitor. ERK-MYD88 interaction inhibitor 1 can induce an HRI-mediated integrated stress response (ISR), leading to cancer cell-specific immunogenic cell apoptosis (apoptosis). ERK-MYD88 interaction inhibitor 1 can induce anti-tumor T cell responses in Lewis lung cancer mice, exhibiting anti-tumor activity[1]. | [References]
[1] Virard F, et al. Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death. Nat Commun. 2024 Aug 15;15(1):7037. DOI:10.1038/s41467-024-51275-z |
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