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221660-80-6

221660-80-6 Structure

221660-80-6 Structure
IdentificationBack Directory
[Name]

1-Piperazineacetonitrile, 4-cyclohexyl-α-[4-[(S)-(4-methoxyphenyl)sulfinyl]phenyl]-
[CAS]

221660-80-6
[Synonyms]

SCH57790
SCH-57790
SCH 57790
1-Piperazineacetonitrile, 4-cyclohexyl-α-[4-[(S)-(4-methoxyphenyl)sulfinyl]phenyl]-
[Molecular Formula]

C25H31N3O2S
[MOL File]

221660-80-6.mol
[Molecular Weight]

437.6
Chemical PropertiesBack Directory
[Boiling point ]

599.3±50.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[pka]

7.73±0.70(Predicted)
Hazard InformationBack Directory
[Description]

SCH 57790 is a selective muscarinic M(2) receptor antagonist, which releases acetylcholine and produces cognitive enhancement.
[Uses]

SCH 57790 is a selective antegonist for muscarinic M2 receptor, which increases acetylcholine release, and thus improves cognitive performance. SCH 57790 reverses Scopolamine (HY-N0296)-induced memory deficits in mice, without significant toxicity (100 mg/kg).
[References]

[1] Carey GJ, et al., SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals. Eur J Pharmacol. 2001 Nov 16;431(2):189-200. DOI:10.1016/s0014-2999(01)01440-6
Spectrum DetailBack Directory
[Spectrum Detail]

1-Piperazineacetonitrile, 4-cyclohexyl-α-[4-[(S)-(4-methoxyphenyl)sulfinyl]phenyl]-(221660-80-6)1HNMR
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