| Identification | Back Directory | [Name]
NORSWERTIANIN | [CAS]
22172-15-2 | [Synonyms]
Norswetianin
NORSWERTIANIN
Norswertianine
1,2,6,8-Tetrahydroxyxanthone
1,2,6,8-Tetrahydroxy-9H-xanthen-9-one
1,3,7,8-Tetrahydroxy-9H-xanthene-9-one
9H-Xanthen-9-one, 1,2,6,8-tetrahydroxy- | [Molecular Formula]
C13H8O6 | [MOL File]
22172-15-2.mol | [Molecular Weight]
260.2 |
| Chemical Properties | Back Directory | [Boiling point ]
601.7±55.0 °C(Predicted) | [density ]
1.766±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.54±0.20(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1]. | [Definition]
ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 2, 6 and 8. | [References]
[1] Gordana Tovilovic-Kovacevic, et al. Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line. Phytomedicine DOI:10.1016/j.phymed.2018.03.052 |
|
|