| Chemical Properties | Back Directory | [density ]
1.48±0.1 g/cm3(Predicted) | [Sequence]
Tyr-Cys-Gln-Lys-Trp-Met-Trp-Thr-Cys-Asp-Ser-Ala-Arg-Lys-Cys-Cys-Glu-Gly-Leu-Val-Cys-Arg-Leu-Trp-Cys-Lys-Lys-Ile-Ile-NH2 (Disulfide bridge: Cys2-Cys16; Cys9-Cys21; Cys15-Cys25) |
| Hazard Information | Back Directory | [Uses]
Phrixotoxin 1, from the venom of the theraphosid spider Phrixotrichus auratus, is a specific peptide inhibitor of Kv4 potassium channel[1][2]. | [References]
[1] Benjamin Chagot, et al. Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider?Phrixotrichus auratus. Protein Sci. 2004 May;13(5):1197-208. DOI:10.1110/ps.03584304
[2] Grit Schaarschmidt, et al. Characterization of Voltage-Gated Potassium Channels in Human Neural Progenitor Cells. PLoS One. 2009 Jul 8;4(7):e6168. DOI:10.1371/journal.pone.0006168
[3] Ryota Imai, et al. Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.3. Biosci Biotechnol Biochem. 2019 Feb;83(2):202-211. DOI:10.1080/09168451.2018.1537773 |
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Alomone Labs
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4008-168-068 13121892008 |
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www.alomone.com |
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