| Identification | Back Directory | [Name]
L-Lysine, L-prolyl-L-valyl-L-leucyl-L-α-aspartyl-L-leucyl-L-phenylalanyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-asparaginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-alanyl-L-leucyl-L-lysyl-L-glutaminyl-L-lysyl-L-leucyl- | [CAS]
221882-20-8 | [Synonyms]
ApoA-I mimetic peptide
L-Lysine, L-prolyl-L-valyl-L-leucyl-L-α-aspartyl-L-leucyl-L-phenylalanyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-asparaginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-alanyl-L-leucyl-L-lysyl-L-glutaminyl-L-lysyl-L-leucyl- | [Molecular Formula]
C122H208N30O33 | [MOL File]
221882-20-8.mol | [Molecular Weight]
2623.18 |
| Chemical Properties | Back Directory | [density ]
1.38±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white | [Sequence]
Pro-Val-Leu-Asp-Leu-Phe-Arg-Glu-Leu-Leu-Asn-Glu-Leu-Leu-Glu-Ala-Leu-Lys-Gln-Lys-Leu-Lys |
| Hazard Information | Back Directory | [Uses]
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex[1][2]. | [References]
[1] Helsingin yliopisto. Formation of therapeutic hdl-mimetic nanodiscs and their interaction with lecithin:cholesterol acyltransferase-a qcm study.
[2] Emily E Morin, et al. Abstract 335: Atheroma-specific Delivery of Synthetic High-density Lipoprotein Containing Sphingosine-1-phosphate for Modulation of Vascular Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. |
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