ChemicalBook--->CAS DataBase List--->2219323-96-1

2219323-96-1

Request For Quotation
2219323-96-1 Structure

2219323-96-1 Structure
IdentificationBack Directory
[Name]

mTOR inhibitor-2
[CAS]

2219323-96-1
[Synonyms]

mTOR inhibitor-2
mTOR inhibitor2,mTOR inhibitor 2
1-Piperidineacetonitrile, 4-[9-(6-amino-3-pyridinyl)-2-oxopyrazino[2,3-c]quinolin-1(2H)-yl]-
[Molecular Formula]

C23H21N7O
[MDL Number]

MFCD31813632
[MOL File]

2219323-96-1.mol
[Molecular Weight]

411.46
Chemical PropertiesBack Directory
[Boiling point ]

684.2±65.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[pka]

5.62±0.26(Predicted)
Hazard InformationBack Directory
[Uses]

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
[IC 50]

mTOR: 7 nM (IC50)
[References]

[1] Guo Q, et al. Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer. J Med Chem. 2018 Feb 8;61(3):881-904. DOI:10.1021/acs.jmedchem.7b01402
2219323-96-1 suppliers list
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
Telephone: 028-81700200 18116577057
Website: https://www.weikeqi-biotech.com/
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Telephone: 13816613772
Website: https://www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Telephone: hanfangpharma@126.com 18017580634
Website: hanfangpharma@126.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Tags:2219323-96-1 Related Product Information
915019-65-7 1009298-59-2 53123-88-9 657-24-9 146986-50-7 2417489-10-0