| Identification | Back Directory | [Name]
mu-1,5-pentanediyldilithium | [CAS]
2223-58-7 | [Synonyms]
Dilithium pentane
1,5-Pentanediyldilithium
mu-1,5-pentanediyldilithium | [EINECS(EC#)]
218-738-9 | [Molecular Formula]
C5H10Li2 | [MOL File]
2223-58-7.mol |
| Hazard Information | Back Directory | [Uses]
Used as constructing block agent: transformations of carboxyl groups and metal halides into cyclohexane and metallacyclohexane synthetic intermediates, and α,ο-bifunctional compounds; in presence of CuI ion, the reagent is transformed into an organobiscuprate. | [Preparation]
1,5-Dilithiopentane was first prepared by direct reaction of 1,5-dibromopentane with Lithium metal at 0 °C in anhydrous ether. This method was later improved by using lithium metal (4 equiv) containing 1% Na with 1,5-dichloropentane (1 equiv). The optimum procedure uses a 12.5% excess of lithium and maintains the temperature at 0 °C (eq 1). Yields up to 90% can be obtained by this method, which may also serve to prepare lower analogs. |
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