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22232-64-0

22232-64-0 Structure

22232-64-0 Structure
IdentificationBack Directory
[Name]

(+/-)-VESAMICOL HYDROCHLORIDE
[CAS]

22232-64-0
[Synonyms]

AH5183 HCL
23965-53-9 (Hydrochloride)
(+/-)-VESAMICOL HYDROCHLORIDE
2-(4-Phenylpiperidino)cyclohexanol
2-(4-Phenyl-1-piperidinyl)cyclohexanol
Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-
(+/-)-TRANS-2-(4-PHENYLPIPERIDINYL)CYCLOHEXANOL HYDROCHLORIDE
[Molecular Formula]

C17H25NO
[MDL Number]

MFCD00477661
[MOL File]

22232-64-0.mol
[Molecular Weight]

259.39
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Vesamicol is a compound used to synthesize radiolabeled derivatives that can be used as sigma receptor ligands for tumor targeting inhibition and have shown certain potential in cellular uptake, biodistribution and inhibition experiments.
[Definition]

ChEBI: 2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines.
[Biological Activity]

Inhibitor of acetylcholine transport (K i = 2 nM). Centrally active following systemic administration in vivo .
[References]

[1] Astatine-211-labeled aza-vesamicol derivatives as sigma receptor ligands for targeted alpha therapy DOI:10.1016/j.nucmedbio.2023.108369
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