| Identification | Back Directory | [Name]
Afatinib Impurity des-EJA | [CAS]
2223677-64-1 | [Synonyms]
Afatinib des-EJA
Afatinib Impurity des-EJA
Des(dimethylamino)-Afatinib
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-, (2E)-
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity) | [Molecular Formula]
C22H20ClFN4O3 | [MOL File]
2223677-64-1.mol | [Molecular Weight]
442.87 |
| Chemical Properties | Back Directory | [Boiling point ]
651.5±55.0 °C(Predicted) | [density ]
1.420±0.06 g/cm3(Predicted) | [pka]
12.48±0.43(Predicted) | [InChIKey]
IRSLBGKNPBBZSA-HSWBROFVSA-N | [SMILES]
C(NC1C(O[C@H]2CCOC2)=CC2C(C=1)=C(NC1=CC=C(F)C(Cl)=C1)N=CN=2)(=O)/C=C/C |
| Hazard Information | Back Directory | [Uses]
Des(dimethylamino)-Afatinib is an impurity of Afatinib . Afatinib is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
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