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22244-14-0

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22244-14-0 Structure

22244-14-0 Structure
IdentificationBack Directory
[Name]

NSC8679
[CAS]

22244-14-0
[Synonyms]

Ferristatin II
Direct Black 38 free acid
[Molecular Formula]

C34H27N9O7S2
[MDL Number]

MFCD00036180
[MOL File]

22244-14-0.mol
[Molecular Weight]

737.76
Chemical PropertiesBack Directory
[density ]

1.61±0.1 g/cm3(Predicted)
[pka]

-0.95±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Direct Black 38 free acid is an azo dye. Direct Black 38 induces unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats in vivo[1].
[References]

[1] Beije B. Induction of unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats exposed in vivo to the benzidine-derived azo dye, Direct Black 38. Mutat Res. 1987 Apr;187(4):227-34. DOI:10.1016/0165-1218(87)90041-3
[2] Byrne SL, et al. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS One. 2013 Jul 23;8(7):e70199. DOI:10.1371/journal.pone.0070199
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