ChemicalBook--->CAS DataBase List--->22255-07-8

22255-07-8

22255-07-8 Structure

22255-07-8 Structure
IdentificationBack Directory
[Name]

Methyl hydroxyangolensate
[CAS]

22255-07-8
[Synonyms]

Methyl hydroxyangolensate
hydroxyangolensateMethyl 6-
Methyl 6-hydroxyangolensate
(13α,17aα)-1α,14β:21,23-Diepoxy-6-hydroxy-4,4-dimethyl-3,16-dioxo-D-homo-24-nor-17-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylic acid methyl ester
(13α,17aα)-6-Hydroxy-1α,14β:21,23-diepoxy-4,4-dimethyl-3,16-dioxo-D-homo-24-nor-17-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylic acid methyl ester
7,12a-Methano-2H,4H-pyrano[4,3-b][1]benzoxocin-8-acetic acid, 4-(3-furanyl)dodecahydro-α-hydroxy-4a,7a,9,9-tetramethyl-13-methylene-2,10-dioxo-, methyl ester, (αS,4S,4aS,7R,7aR,8R,11aS,12aS)-
[Molecular Formula]

C27H34O8
[MDL Number]

MFCD20261038
[MOL File]

22255-07-8.mol
[Molecular Weight]

486.56
Chemical PropertiesBack Directory
[Melting point ]

252 °C
[Boiling point ]

630.0±55.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

12.47±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

6-Methylhydroxyyangolensate is a limonoid can be extracted from Khaya grandifoliola. 6-Methylhydroxyyangolensate has low antimalarial activity in vitro, with an IC50 of 21.59 μg/ml against P. falciparum (W2/Indochina clone)[1].
[References]

[1] Bickii J, et al. In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae). J Ethnopharmacol. 2000 Jan;69(1):27-33. DOI:10.1016/s0378-8741(99)00117-8
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