| Identification | Back Directory | [Name]
Q151 | [CAS]
2226449-95-0 | [Synonyms]
Q151
Propanamide, N-[2-(4-cyanophenyl)-5-benzoxazolyl]-2-[(2,3-difluorophenyl)amino]-, (2S)- | [Molecular Formula]
C23H16F2N4O2 | [MDL Number]
MFCD32063537 | [MOL File]
2226449-95-0.mol | [Molecular Weight]
418.4 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [color ]
white to beige | [InChI]
1S/C23H16F2N4O2/c1-13(27-18-4-2-3-17(24)21(18)25)22(30)28-16-9-10-20-19(11-16)29-23(31-20)15-7-5-14(12-26)6-8-15/h2-11,13,27H,1H3,(H,28,30)/t13-/m0/s1 | [InChIKey]
QUSYLBPSSGPXBL-ZDUSSCGKSA-N | [SMILES]
FC1=C(N[C@@H](C)C(NC2=CC(N=C(C3=CC=C(C#N)C=C3)O4)=C4C=C2)=O)C=CC=C1F |
| Hazard Information | Back Directory | [Biological Activity]
Q151 is an inhibitor of bacterial inosine 5μ-monophosphate dehydrogenase 2 (IMPDH2) with an IC50 value of 18 nM. It does not inhibit human IMPDH |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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