| Chemical Properties | Back Directory | [Boiling point ]
979.0±65.0 °C(Predicted) | [solubility ]
DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 0.15 mg/ml | [form ]
A crystalline solid | [pka]
4.24±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
TCEP-biotin is biotinylated form of the reducing agent TCEP and an affinity probe for protein lysine crotonylation.1 Covalent addition of the TCEP moiety to crotonylated lysine residues results in adduct formation that allows for detection or immobilization of crotonylated proteins through interaction with the biotin ligand. It has been used in the detection and isolation of crotonylated histones in HEK293 cells. | [Uses]
TCEP-biotin is biotinylated TCEP (HY-W011500). TCEP-biotin is also a probe for histone lysine crotonylation[1]. | [References]
1. Bos, J., and Muir, T.W. A chemical probe for protein crotonylation J. Am. Chem. Soc. 140(14),4757-1760(2018). |
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| Company Name: |
commedx
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| Tel: |
010-46598925 18519000250 |
| Website: |
http://www.commedx.com |
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