ChemicalBook--->CAS DataBase List--->2227211-00-7

2227211-00-7

2227211-00-7 Structure

2227211-00-7 Structure
IdentificationBack Directory
[Name]

AS-1763
[CAS]

2227211-00-7
[Synonyms]

AS-1763
[Molecular Formula]

C33H31FN6O3
[MOL File]

2227211-00-7.mol
[Molecular Weight]

578.65
Spectrum DetailBack Directory
[Spectrum Detail]

AS-1763(2227211-00-7)1HNMR
Hazard InformationBack Directory
[Biological Activity]

AS-1763 is a potent, selective, noncovalent, and orally available inhibitor of Bruton’s tyrosine kinase (IC50 = 0.85 nM).
[References]

[1]. Kawahata W, et al. Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton’s Tyrosine Kinase. J Med Chem. 2021 Oct 14;64(19):14129-14141.
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