| Identification | Back Directory | [Name]
2-(2,6-dioxopiperidin-3-yl)-5-(piperidin-4-yl)isoindoline-1,3-dione hydrochloride | [CAS]
2229718-44-7 | [Synonyms]
2-(2,6-dioxopiperidin-3-yl)-5-(piperidin-4-yl)isoindole-1,3-dione hydrochloride
2-(2,6-dioxopiperidin-3-yl)-5-(piperidin-4-yl)isoindoline-1,3-dione hydrochloride | [Molecular Formula]
C18H19N3O4.ClH | [MOL File]
2229718-44-7.mol | [Molecular Weight]
377.82 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
powder | [InChI]
1S/C18H19N3O4/c22-15-4-3-14(16(23)20-15)21-17(24)12-2-1-11(9-13(12)18(21)25)10-5-7-19-8-6-10/h1-2,9-10,14,19H,3-8H2,(H,20,22,23) | [InChIKey]
KOGMQASWKIDFRN-UHFFFAOYSA-N | [SMILES]
N1CCC(CC1)c2cc3c(cc2)C(=O)N(C3=O)C4CCC(=O)NC4=O |
| Hazard Information | Back Directory | [Uses]
A functionalized cereblon ligand for development of Thalidomide based PROTACs. Allows rapid conjugation with carboxyl linkers due to presence of amine group via peptide coupling reactions. Amenable for linker attachement via reductive amination, and a basic building block for making protein degrader library.
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| Company Name: |
ChemShuttle, Inc.
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| Telephone: |
0510-83588313-811 18800520310 |
| Website: |
www.jiehuapharma.com/ |
| Company Name: |
Pharmalego
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| Telephone: |
18321033991 |
| Website: |
https://cn.pharmalego.com/ |
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