| Chemical Properties | Back Directory | [Boiling point ]
469.978±35.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.104±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid-Liquid Mixture | [pka]
10.009±0.15(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling[1]. | [Biological Activity]
Tyramide alkyne (Alkyne-phenol 1) is a cell penetrant and highly efficient clickable ascorbate peroxidase 2 (APEX2) substrate th at significantly improves APEX-labeling efficiency in intact yeast cells. Tyramide alkyne enable biotin-independent detection of labeled proteins. | [References]
[1] Ganapathy US, et al. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infect Dis. 2018 Jun 8;4(6):918-925. DOI:10.1021/acsinfecdis.8b00044 |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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