| Identification | Back Directory | [Name]
Tuberculosis inhibitor 1 | [CAS]
2230810-28-1 | [Synonyms]
Tuberculosis inhibitor 1
Ethanone, 2-(5-methoxy-2-methyl-1H-indol-3-yl)-1-[2-[5-(2-naphthalenyl)-1H-imidazol-2-yl]-4-[(tetrahydro-3-furanyl)methyl]-1-piperazinyl]- | [Molecular Formula]
C34H37N5O3 | [MDL Number]
MFCD32067930 | [MOL File]
2230810-28-1.mol | [Molecular Weight]
563.69 |
| Chemical Properties | Back Directory | [Boiling point ]
873.8±65.0 °C(Predicted) | [density ]
1.276±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
13.71±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1]. | [References]
[1] Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692. DOI:10.1016/j.bmcl.2018.10.028 |
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