| Identification | Back Directory | [Name]
Sulfamide, N-[2-[1-(2-amino-6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]ethyl]- | [CAS]
2230916-95-5 | [Synonyms]
Enpp-1-IN-5
Sulfamide, N-[2-[1-(2-amino-6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]ethyl]- | [Molecular Formula]
C17H26N6O4S | [MOL File]
2230916-95-5.mol | [Molecular Weight]
410.49 |
| Chemical Properties | Back Directory | [Boiling point ]
680.1±65.0 °C(Predicted) | [density ]
1.351±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.00±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-5 has the potential for the research of cancer and infectious diseases (extracted from patent WO2019046778A1/WO2021203772A1, compound 1)[1][2]. | [References]
[1] William Michael Gallatin, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof. Patent WO2019046778A1.
[2] Bang Fu, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 inhibitors,compositions and uses thereof. Patent WO2021203772A1. |
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