| Identification | Back Directory | [Name]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 (trifluoroacetate salt) | [CAS]
2237216-67-8 | [Synonyms]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 (trifluoroacetate salt) |
| Hazard Information | Back Directory | [Description]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).1 Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.WARNING This product is not for human or veterinary use. | [References]
[1] SHAINA R. ECKHOUSE MD , PHD. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia–reperfusion: Relationship to interstitial microRNA dynamics and myocardial function[J]. Journal of Thoracic and Cardiovascular Surgery, 2013, 145 1: Pages 267-277.e4. DOI: 10.1016/j.jtcvs.2012.09.071 |
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