| Identification | Back Directory | [Name]
4-Pyridinecarboxaldehyde, 2-(2-pyridinyl)hydrazone, [C(E)]- | [CAS]
2241017-37-6 | [Synonyms]
Isonicotinaldehyde 2-pyridin
Isonicotinaldehyde 2-pyridinylhydrazone
4-Pyridinecarboxaldehyde, 2-(2-pyridinyl)hydrazone, [C(E)]-
4-[(1e)-[2-(pyridin-2-yl)hydrazin-1-ylidene]methyl]pyridine | [Molecular Formula]
C11H10N4 | [MOL File]
2241017-37-6.mol | [Molecular Weight]
198.23 |
| Hazard Information | Back Directory | [Uses]
Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action[1]. | [References]
[1] Synthesis, Biological Activity, and Mechanism of Action of 2-Pyrazyl and Pyridylhydrazone Derivatives, New Classes of Antileishmanial Agents |
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