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2241669-05-4

2241669-05-4 Structure

2241669-05-4 Structure
IdentificationBack Directory
[Name]

Propanamide, 2-(acetylamino)-3-[[2-amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]-N-(21-chloro-3,6,9,12,15-pentaoxaheneicos-1-yl)-, (2R)-
[CAS]

2241669-05-4
[Synonyms]

Mitochondria degrader-1
Propanamide, 2-(acetylamino)-3-[[2-amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]-N-(21-chloro-3,6,9,12,15-pentaoxaheneicos-1-yl)-, (2R)-
[Molecular Formula]

C33H49ClFN7O8S
[MOL File]

2241669-05-4.mol
[Molecular Weight]

758.3
Chemical PropertiesBack Directory
[density ]

1.35±0.1 g/cm3(Predicted)
[form ]

Oil
[pka]

13.84±0.46(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Mitochondria degrader-1 (example 5) is a potent mitochondria degrader. Mitochondria degrader-1 induces the degradation of the injured mitochondria by the autophagy mechanism. Mitochondria degrader-1 can be used for the research of neurodegenerative disease, cancer, inflammatory disease, age-related disease, metabolic disease, mitochondrial disease or Down's disease[1].
[References]

[1] Boyi Youben, et al. Degradation agent by autophagy mechanism of injured mitochondria. JPWO2019013181A1.
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