| Hazard Information | Back Directory | [Uses]
Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection[1]. | [in vivo]
Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) protects mice against lethal challenge with MRSA in a bacteremia model[1]. | Animal Model: | Balb/C mice with MRSA in a bacteremia model[1] | | Dosage: | 2.5 mg/mice and 10 mg/mice | | Administration: | Intravenous injection | | Result: | Increased mouse Balb/C mice with MRSA in a bacteremia model survival. |
| [References]
[1] Varshney AK, et, al. A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia. PLoS One. 2018 Jan 24;13(1):e0190537. DOI:10.1371/journal.pone.0190537 |
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Biolab Reagents
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Cell Sciences
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www.cellsciences.com |
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