| Identification | Back Directory | [Name]
PI3Kdelta inhibitor 1 | [CAS]
2242109-74-4 | [Synonyms]
PI3Kdelta inhibitor 1,PI-3Kdelta inhibitor 1 | [Molecular Formula]
C27H38N6O5S | [MDL Number]
MFCD32641129 | [MOL File]
2242109-74-4.mol | [Molecular Weight]
558.69 |
| Chemical Properties | Back Directory | [Boiling point ]
703.2±70.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
6.03±0.50(Predicted) |
| Hazard Information | Back Directory | [Description]
PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM[1].
PI3Kδ|1.3 nM (IC50)
| [Uses]
PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM[1]. | [IC 50]
PI3Kδ: 1.3 nM (IC50) | [storage]
Store at -20°C | [References]
[1]. Hamajima T, et al. Optimization and in vivo evaluation of pyrazolopyridines as a potent and selective PI3Kδ inhibitor. Bioorg Med Chem. 2018 Aug 7;26(14):3917-3924. |
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