| Identification | Back Directory | [Name]
5α-Androstane-3,6,17-trione | [CAS]
2243-05-2 | [Synonyms]
5α-Androstan-3,6,17-trione
(5α)-Androstane-3,6,17-trione
Androstane-3,6,17-trione, (5α)- | [Molecular Formula]
C19H26O3 | [MDL Number]
MFCD00199604 | [MOL File]
2243-05-2.mol | [Molecular Weight]
302.41 |
| Chemical Properties | Back Directory | [Melting point ]
188.5-190.5 °C | [Boiling point ]
452.2±45.0 °C(Predicted) | [density ]
1.147±0.06 g/cm3(Predicted) | [solubility ]
DMF: 50 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 30 mg/mL; Ethanol: 5 mg/mL | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
5α-Androstan-3,6,17-trione is an analog of 4-androstene-3,6,17-trione (4-AT, 6-OXO), an irreversible aromatase inhibitor that is used to increase serum androgen levels. 5α-Androstan-3,6,17-trione is considered a designer drug and is regulated in the United States. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications. | [Uses]
(5α)-Androstane-3,6,17-trione is identified as biotransformation products of testosterone. Also, it is an aromatase inhibitor in human placental microsomes. | [References]
[1] MITSUTERU NUMAZAWA Ayako M Masachika Tsuji. Studies on aromatase inhibition with 4-androstene-3,6,17-trione: Its 3β-reduction and time-dependent irreversible binding to aromatase with human placental microsomes[J]. Journal of steroid biochemistry, 1987, 28 3: Pages 337-344. DOI: 10.1016/0022-4731(87)91028-4
[2] DAN ROHLE. Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained, eugonadal males.[J]. Journal of the International Society of Sports Nutrition, 2007, 4: 13. DOI: 10.1186/1550-2783-4-13 |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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