| Identification | Back Directory | [Name]
L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl- | [CAS]
2243207-00-1 | [Synonyms]
α-Synuclein Binding?Peptide?trifluoroacetate salt
L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl- | [Molecular Formula]
C45H80N14O14 | [MOL File]
2243207-00-1.mol | [Molecular Weight]
1041.22 |
| Chemical Properties | Back Directory | [Boiling point ]
1532.8±65.0 °C(Predicted) | [density ]
1.241±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.21±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH? |
| Hazard Information | Back Directory | [Uses]
α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1]. | [IC 50]
α-synuclein Aggregation | [References]
[1] Torpey J H, et al. Insights into peptide inhibition of alpha-synuclein aggregation[J]. Frontiers in Neuroscience, 2020, 14: 561462. |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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