| Identification | Back Directory | [Name]
m-PEG3-triethoxysilane | [CAS]
2243566-45-0 | [Synonyms]
m-PEG3-triethoxysilane
m-PEG3-amido-C3-triethoxysilane | [Molecular Formula]
C17H37NO7Si | [MDL Number]
MFCD31693729 | [MOL File]
2243566-45-0.mol | [Molecular Weight]
395.56 |
| Chemical Properties | Back Directory | [Boiling point ]
471.6±40.0 °C(Predicted) | [density ]
1.016±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [pka]
15.75±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
m-PEG3-triethoxysilane is a PEG linker containing a triethoxysilane moiety. Triethoxysilane is commonly used for surface modifications. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous media. The water solubility properties of the PEG linkers are enhanced with longer PEG chains. | [Uses]
m-PEG3-amido-C3-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
|
|