| Identification | Back Directory | [Name]
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- | [CAS]
2243736-37-8 | [Synonyms]
MUN36378
FTO inhibitor 1
Benzoic acid, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]- | [Molecular Formula]
C18H15Cl2N3O2 | [MOL File]
2243736-37-8.mol | [Molecular Weight]
376.24 |
| Chemical Properties | Back Directory | [Boiling point ]
523.0±50.0 °C(Predicted) | [density ]
1.439±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.58±0.36(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
MUN36378 is a FTO inhibitor for treatment of leukemia. This compound was first reported in patent WO 2018157842. This product has no formal name at the moment. | [Uses]
FTO-IN-7 is an inhibitor of FTO. FTO-IN-7 can be used in study Alzheimer's diseases, breast cancers, small-cell lung cancers,a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma[1]. | [References]
[1] Yang, Caiguang, et al.Preparation of 2-substituted-benzene matrix
compounds as FTO inhibitors.China,WO2018157843.2018-09-07.
[2] Liu Z, Duan Z, Zhang D, et al. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022;65(15):10638-10654. DOI:10.1021/acs.jmedchem.2c00848 |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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