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2247047-81-8

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2247047-81-8 Structure

2247047-81-8 Structure
IdentificationBack Directory
[Name]

EV206
[CAS]

2247047-81-8
[Synonyms]

EV206
Hazard InformationBack Directory
[Uses]

EV206 is a potent Hsp70 inhibitor. EV206 shows antiproliferative activity. EV206 induces apoptosis and increases the protein expression of cleaved PARP and caspase-3. EV206 shows antitumor activity[1].
[IC 50]

HSP70
[References]

[1] Min HY, et al. Development of a novel N14-substituted antitumor evodiamine derivative with inhibiting heat shock protein 70 in non-small cell lung cancer. Sci Rep. 2024 Oct 25;14(1):25436. DOI:10.1038/s41598-024-74926-z
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