| Identification | Back Directory | [Name]
Ethanesulfonamide, N,N-dimethyl-2-[(5-quinolinylmethyl)amino]- | [CAS]
2248852-19-7 | [Synonyms]
UCSF686
UCSF648 dihydrochloride
Ethanesulfonamide, N,N-dimethyl-2-[(5-quinolinylmethyl)amino]- | [Molecular Formula]
C14H19N3O2S | [MOL File]
2248852-19-7.mol | [Molecular Weight]
293.38 |
| Hazard Information | Back Directory | [Uses]
UCSF686 is a probe with which to study the function of the 5-HT5AR. UCSF686 loses affinity at 5-HT5AR (>10?000 nM) but not at 5-HT1AR, 5-HT2BR, and 5-HT7R. UCSF686 controls for off-target effects[1]. | [References]
[1] Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022;65(5):4201-4217. DOI:10.1021/acs.jmedchem.1c02031 |
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