| Identification | Back Directory | [Name]
(3S,5R)-XU 62-320 D6 | [CAS]
2249799-35-5 | [Synonyms]
(3S,5R)-XU 62-320 D6
(3S,5R)-Fluvastatin D6 sodium | [Molecular Formula]
C24H27FNNaO4 | [MDL Number]
MFCD11978006 | [MOL File]
2249799-35-5.mol | [Molecular Weight]
435.47 |
| Hazard Information | Back Directory | [Uses]
(3S,5R)-Fluvastatin-d6 (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1]. | [References]
[1] Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. DOI:10.1111/apm.12031 |
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