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RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1]. | [References]
[1] WATERSON, Alex G, et al. QUINAZOLINE COMPOUNDS AS MODULATORS OF RAS SIGNALING. Patent. WO2018212774A1. |
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