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2253640-49-0

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2253640-49-0 Structure

2253640-49-0 Structure
IdentificationBack Directory
[Name]

PKC-theta inhibitor hcl
[CAS]

2253640-49-0
[Synonyms]

PKC-theta inhibitor hcl
PKC theta inhibitor hcl,PKCtheta inhibitor hcl
[Molecular Formula]

C20H25F3N6O3.ClH
[MOL File]

2253640-49-0.mol
[Molecular Weight]

490.91
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313
Hazard InformationBack Directory
[Uses]

PKC-theta inhibitor 2 hydrochloride is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1].
[storage]

Store at -20°C
[References]

[1] Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30. DOI:10.1016/j.bmcl.2006.09.056
Spectrum DetailBack Directory
[Spectrum Detail]

PKC-theta inhibitor hcl(2253640-49-0)1HNMR
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