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2253996-73-3

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2253996-73-3 Structure

2253996-73-3 Structure
IdentificationBack Directory
[Name]

Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]-
[CAS]

2253996-73-3
[Synonyms]

Antiparasitic agent-6
Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]-
[Molecular Formula]

C19H15N3O3
[MOL File]

2253996-73-3.mol
[Molecular Weight]

333.34
Chemical PropertiesBack Directory
[Boiling point ]

577.4±60.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

11.78±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM)[1].
[References]

[1] Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418. DOI:10.1016/j.ejmech.2020.112418
2253996-73-3 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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