ChemicalBook--->CAS DataBase List--->2254118-43-7

2254118-43-7

2254118-43-7 Structure

2254118-43-7 Structure
IdentificationBack Directory
[Name]

Upifitamab
[CAS]

2254118-43-7
[Synonyms]

Upifitamab
Research Grade Upifitamab(DHB65402)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Upifitamab is an ADC Antibody (a naked antibody of upifitamab rilsodotin), which can be used for antibody-coupled agent (ADC) synthesis. Upifitamab rilsodotin is an ADC targeting NaPi2b and is used in ovarian cancer research, particularly in platinum-resistant recurrent ovarian cancer[1].
[References]

[1] Richardson D, et al. Updated Results from the Phase 1 Expansion Study of Upifitamab Rilsodotin (UpRi; XMT-1536), a NaPi2b-directed Dolaflexin Antibody Drug Conjugate (ADC) in Ovarian Cancer (076). Gynecologic Oncology, 2022, 166: S48.
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