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2259318-54-0

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2259318-54-0 Structure

2259318-54-0 Structure
IdentificationBack Directory
[Name]

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
[CAS]

2259318-54-0
[Synonyms]

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
[Molecular Formula]

C70H83N9O22
[MDL Number]

MFCD32263395
[MOL File]

2259318-54-0.mol
[Molecular Weight]

1402.46
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

7.33±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
[References]

[1] John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1
2259318-54-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Website: www.bio-fount.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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