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2277-43-2

2277-43-2 Structure

2277-43-2 Structure
IdentificationBack Directory
[Name]

(-)-2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]pteridine-4(1H)-one
[CAS]

2277-43-2
[Synonyms]

L-Neopterin
(-)-L-Neopterin
Neopterin, L-(-)-
L-erythro-Neopterin
Neopterin, L-erythro-
Neopterin, L erythro ,Neopterin, Lerythro
4(1H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2,3-trihydroxypropyl]-
(-)-2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]pteridine-4(1H)-one
[Molecular Formula]

C9H11N5O4
[MOL File]

2277-43-2.mol
[Molecular Weight]

253.21
Chemical PropertiesBack Directory
[Melting point ]

>300 °C
[Boiling point ]

590.4±60.0 °C(Predicted)
[density ]

2.02±0.1 g/cm3(Predicted)
[pka]

12.60±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

L-(-)-Neopterin (L-erythro-Neopterin) is a cholinergic receptor that acts as a competitive antagonist, countering the inhibitory effects of pteridine diuretics on the growth of Crithidia fasciculata. L-(-)-Neopterin can be used in research related to the nervous system and purine metabolism[1].
[References]

[1] Dewey VC, et al. Pteridine diuretics as biopterin antagonists. Biochem Pharmacol. 1974 Feb 15;23(4):773-9. DOI:10.1016/0006-2952(74)90207-x
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