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2279945-77-4

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2279945-77-4 Structure

2279945-77-4 Structure
IdentificationBack Directory
[Name]

Glucocerebrosidase-IN-1 hydrochloride
[CAS]

2279945-77-4
[Synonyms]

Glucocerebrosidase-IN-1 hydrochloride
Hazard InformationBack Directory
[Uses]

Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1].
[References]

[1] Clemente F, et al. Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning. Bioorg Chem. 2020 May;98:103740. DOI:10.1016/j.bioorg.2020.103740
2279945-77-4 suppliers list
Company Name: TargetMol Chemicals Inc.  
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Website: https://www.targetmol.cn/
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