| Hazard Information | Back Directory | [Uses]
N3-VC-PAB-PNP is the intermediate of bicyclic peptide ligand STING conjugates[1]. N3-VC-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] McDonnell, et al. Preparation of bicyclic peptide ligand STING conjugates and uses thereof. World Intellectual Property Organization, WO2020165600 A1. 2020-08-20. |
|
|