| Identification | Back Directory | [Name]
2'-Amino-2'-deoxy-5-fluoro-arabinouridine | [CAS]
2305415-81-8 | [Synonyms]
2'-Amino-2'-deoxy-5-fluoro-arabinouridine
2’-Amino-2’-deoxy-5-fluoro-arabinouridine | [Molecular Formula]
C9H12FN3O5 | [MDL Number]
MFCD31814064 | [MOL File]
2305415-81-8.mol | [Molecular Weight]
261.21 |
| Hazard Information | Back Directory | [Uses]
2’-Amino-2’-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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