| Identification | Back Directory | [Name]
2',3'-Bis(O-t-butyldimethylsilyl)-2-thiouridine | [CAS]
2305415-97-6 | [Synonyms]
2',3'-Bis(O-t-butyldimethylsilyl)-2-thiouridine | [Molecular Formula]
C21H40N2O5SSi2 | [MOL File]
2305415-97-6.mol | [Molecular Weight]
488.79 |
| Hazard Information | Back Directory | [Uses]
2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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