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Sotigalimab is a humanized monoclonal antibody agonist of the cell surface receptor CD40, with potential immunostimulatory and antineoplastic activities. | [Pharmacology]
Sotigalimab binds to CD40 on a variety of immune cell types. This triggers the cellular proliferation and activation of antigen-presenting cells (APCs), and activates B cells, and effector and memory T cells. This results in an enhanced immune response against tumor cells. Sotigalimab also binds to and activates CD40 present on the surfaces of some solid tumor cells, leading to apoptosis and decreased tumor growth. |
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| Company Name: |
Biolab Reagents
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027-65279366 18108604356 |
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www.biolabreagent.com/ |
| Company Name: |
Cell Sciences
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9785721070 |
| Website: |
www.cellsciences.com |
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