ChemicalBook--->CAS DataBase List--->23109-94-6

23109-94-6

23109-94-6 Structure

23109-94-6 Structure
IdentificationBack Directory
[Name]

9ALPHA,11ALPHA-DIHYDROXY-15-OXO-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
[CAS]

23109-94-6
[Synonyms]

TETRANOR-PGFM
IGRHJCFWWOQYQE-SYQHCUMBSA-N
TETRANOR PROSTAGLANDIN F METABOLITE
tetranor-PGFM Lipid Maps MS Standard
9ALPHA,11ALPHA-DIHYDROXY-15-OXO-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-3,5-dihydroxy-ε-oxo-, (1R,2R,3S,5R)-
[Molecular Formula]

C16H26O7
[MDL Number]

MFCD07375437
[MOL File]

23109-94-6.mol
[Molecular Weight]

330.37
Chemical PropertiesBack Directory
[solubility ]

DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

tetranor-PGFM is the major urinary metabolite of PGF. Normal healthy females excrete 7-13 μg of tetranor-PGFM per day compared to 11-59 μg/24 hours for healthy males. In pregnant females, tetranor-PGFM levels in the urine are 2 to 5-fold higher and diminish to pre-pregnancy levels soon after labor.
[Uses]

tetranor-PGFM is the major urinary metabolite of Dinoprost (HY-12956)[1].
[Definition]

ChEBI: 2,3,4,5-tetranor-prostaglandin FM is a prostanoid that is prostaglandin E2-UM in which the oxo group at position 9 has been reduced to the corresponding alcohol (alpha-configuration). It has a role as a metabolite. It is a prostanoid, an oxo dicarboxylic acid, a secondary alcohol and a ketone.
[References]

[1] Granstr?m E, et al. The structure of a urinary metabolite of prostaglandin F2a in man. J Am Chem Soc. 1969 Jun 4;91(12):3398-400. DOI:10.1021/ja01040a067
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