| Identification | Back Directory | [Name]
Ac-pSar12-OH | [CAS]
2313534-24-4 | [Synonyms]
Ac-pSar12-OH
3,6,9,12,15,18,21,24,27,30,33,36-Dodecamethyl-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxo-3,6,9,12,15,18,21,24,27,30,33,36-dodecaazaoctatriacontan-1-oic Acid | [Molecular Formula]
C38H64N12O14 | [MOL File]
2313534-24-4.mol | [Molecular Weight]
913 |
| Chemical Properties | Back Directory | [Boiling point ]
1104.2±65.0 °C(Predicted) | [density ]
1.298±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.35±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC)[1][2]. | [References]
[1] Hu Y, et al. Polysarcosine as an Alternative to PEG for Therapeutic Protein Conjugation. Bioconjug Chem. 2018 Jul 18;29(7):2232-2238. DOI:10.1021/acs.bioconjchem.8b00237
[2] Warren VIRICEL, et al. Ligand-drug-conjugate comprising a single molecular weight polysarcosine. Patent. WO2019081455A1. |
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