| Identification | Back Directory | [Name]
5H-Benz[4,5]isoindolo[1,2-c][1,4]benzodiazepine-15-acetic acid, 7-(4-chlorophenyl)-6,7,8,13-tetrahydro-4-methoxy-, ethyl ester | [CAS]
2314380-76-0 | [Synonyms]
5H-Benz[4,5]isoindolo[1,2-c][1,4]benzodiazepine-15-acetic acid, 7-(4-chlorophenyl)-6,7,8,13-tetrahydro-4-methoxy-, ethyl ester | [Molecular Formula]
C31H29ClN2O3 | [MOL File]
2314380-76-0.mol | [Molecular Weight]
513.03 |
| Chemical Properties | Back Directory | [Melting point ]
69-71 °C | [Boiling point ]
697.2±55.0 °C(predicted) | [density ]
1.30±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.69±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
Anti-MRSA agent 12 (Compound SM-5) is an antibiotic, which exhibits antibacterial activity against Staphylococcus aureus, S. epidermidis and Escherichia coli with MIC of 7.81, 7.81 and 62.5 μM. Anti-MRSA agent 12 inhibits the methicillin-resistant S. aureus (MRSA) through inhibition of biofilm formation[1]. | [References]
[1] Mondal SK, et al., Anti-MRSA activity of chlorophenyl pyrrolo benzodiazepines compound. J Antibiot (Tokyo). 2024 Jun 18. DOI:10.1038/s41429-024-00747-x |
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