| Identification | Back Directory | [Name]
6-Prenyl-1H-indole | [CAS]
23158-16-9 | [Synonyms]
6-Prenylindole
Antibiotic 434B
6-Prenyl-1H-indole
6-(3-Methyl-2-butenyl)-1H-indole
6-?(3-?Methyl-?2-?buten-?1-?yl)?-?1H-?indole | [MDL Number]
MFCD18449579 | [MOL File]
23158-16-9.mol |
| Hazard Information | Back Directory | [Description]
6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties. It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (15 and 30 μg/disc in the paper disc assay), and also drug-resistant P. falciparum strain K1 (IC50 = 21 μg/ml). | [Uses]
6-?(3-?Methyl-?2-?buten-?1-?yl)?-?1H-?indole is an antifungal metabolite isolated from Streptomyces. It can also be found in oil of the roots of M. tenuifolia. | [storage]
Store at -20°C | [References]
[1] TOMOMITSU SASAKI. Identification of 6-prenylindole as an antifungal metabolite of Streptomyces sp. TP-A0595 and synthesis and bioactivity of 6-substituted indoles.[J]. Journal of Antibiotics, 2002, 55 11: 1009-1012. DOI: 10.7164/antibiotics.55.1009
[2] MAYUNGA H H NKUNYA Stephan A J John J Makangara. Prenylindoles from Tanzanian Monodora and Isolona species.[J]. Natural Product Research, 2004, 18 3: 253-258. DOI: 10.1080/14786410310001620529 |
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