| Identification | Back Directory | [Name]
(RS)-Butyryltimolol | [CAS]
2320274-78-8 | [Synonyms]
(RS)-Butyryltimolol
Butanoic acid, 1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl ester | [Molecular Formula]
C17H30N4O4S | [MDL Number]
MFCD31544347 | [MOL File]
2320274-78-8.mol | [Molecular Weight]
386.51 |
| Chemical Properties | Back Directory | [Boiling point ]
511.5±50.0 °C(Predicted) | [density ]
1.169±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (258.73 mM) | [form ]
Oil | [pka]
8.74±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol, an effective proagent of Timolol, improves the corneal penetration of Timolol[1]. Butyryltimolol is a β-adrenergic blocker[2]. | [IC 50]
β adrenergic receptor | [storage]
Store at -20°C | [References]
[1] Chang SC, et al. Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol. Exp Eye Res. 1988 Jan;46(1):59-69. DOI:10.1016/s0014-4835(88)80093-9
[2] Potter DE, et al. Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol. Curr Eye Res. 1988 Aug;7(8):755-9. DOI:10.3109/02713688809033206 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|