| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, 2-amino-5-[3-(1-piperazinyl)phenyl]-N-4-pyridinyl- | [CAS]
2328094-11-5 | [Synonyms]
PKC-iota inhibitor 1
3-Pyridinecarboxamide, 2-amino-5-[3-(1-piperazinyl)phenyl]-N-4-pyridinyl- | [Molecular Formula]
C21H22N6O | [MDL Number]
MFCD32062834 | [MOL File]
2328094-11-5.mol | [Molecular Weight]
374.44 |
| Chemical Properties | Back Directory | [Boiling point ]
590.5±50.0 °C(Predicted) | [density ]
1.288±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (333.83 mM; Need ultrasonic) | [form ]
Solid | [pka]
10.49±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ?) inhibitor with an IC50 value of 0.34 μM[1]. | [References]
[1] Kwiatkowski J, et al. Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues. ACS Med Chem Lett. 2019 Feb 15;10(3):318-323. DOI:10.1021/acsmedchemlett.8b00546 |
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