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23294-41-9

23294-41-9 Structure

23294-41-9 Structure
IdentificationBack Directory
[Name]

(+)-Bis[(R)-1-phenylethyl]amine
[CAS]

23294-41-9
[Synonyms]

(R,R)-Bis-(1-phenylethyl)amin
(+)-Bis[(R)-1-phenylethyl]amine
(R)-bis((R)-1-phenylethyl)aMine
(+)-bis[(r)-α-methylbenzyl]amine
(+)-Bis[(R)-1-phenylethyl]amine 99%
(+)-BIS (R)-1-PHENYLETHYL!AMINE HYDRO-
[R-(R*,R*)]-(+)-Bis(α-methylbenzyl)amine
(+)-Bis[(R)-1-phenylethyl]amine, ChiPros
(+)-Bis[(R)-1-phenylethyl]amine, 99% (99+% EE/GLC)
(+)-Bis[(R)-1-phenylethyl]amine, ChiPros 99%, ee 98+%
(+)-Bis[(R)-1-phenylethyl]aMine, ChiPros|r, 99%, ee 98+%
Benzenemethanamine, α-methyl-N-[(1R)-1-phenylethyl]-, (αR)-
(+)-BIS[(R)-1-PHENYLETHYL]AMINE, OR (R)-BIS((R)-1-PHENYLETHYL)AMINE
(+)-Bis[(R)-α-methylbenzyl]amine, [R-(R*,R*)]-(+)-Bis(α-methylbenzyl)amine
[Molecular Formula]

C16H19N
[MDL Number]

MFCD00243088
[MOL File]

23294-41-9.mol
[Molecular Weight]

225.33
Chemical PropertiesBack Directory
[Melting point ]

~260 °C
[alpha ]

199 º (NEAT)
[Boiling point ]

86 °C0.05 mm Hg(lit.)
[density ]

0.985 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.5523(lit.)
[Fp ]

>230 °F
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[pka]

8.79±0.29(Predicted)
[Optical Rotation]

[α]20/D +199.0°, neat
[Water Solubility ]

Insoluble in water.
[BRN ]

3590931
[CAS DataBase Reference]

23294-41-9
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36/37
[WGK Germany ]

3
[F ]

3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethyl acetate-->Tetrahydrofuran-->Dichloromethane-->Toluene-->Acetonitrile-->Sodium borohydride-->p-Toluenesulfonic acid-->Acetophenone-->HEAVY DISTILLATE-->(R)-(+)-1-Phenylethylamine
Hazard InformationBack Directory
[Uses]

(+)-Bis[(R)-1-phenylethyl]amine play a very extensive role of making chirally optically active drugs and compounds. Also as intermediates.
[Uses]

(+)-Bis[(R)-1-phenylethyl]amine can be used:
  • In the synthesis of?β-amino acids.
  • In the preparation of chiral C(19)-C(26) and C(27)-C(32) moieties of scytophycin C.
  • To induce enantioselectivity in the deprotonation of prochiral ketones.
  • As a starting material for the synthesis of chiral phenolate ligands through Mannich condensation reaction.
  • In the synthesis of chiral phosphoramidite ligands.
  • To prepare chiral cyclic isoimidium salts, which are further used to synthesize chiral lactones through Diels-Alder reaction.

Spectrum DetailBack Directory
[Spectrum Detail]

(+)-Bis[(R)-1-phenylethyl]amine(23294-41-9)1HNMR
(+)-Bis[(R)-1-phenylethyl]amine(23294-41-9)IR
(+)-Bis[(R)-1-phenylethyl]amine(23294-41-9)FT-IR
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